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Wednesday, April 29, 2020 | History

3 edition of Bioassay of p-nitrosodiphenylamine for possible carcinogenicity. found in the catalog.

Bioassay of p-nitrosodiphenylamine for possible carcinogenicity.

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  • 7 Currently reading

Published by Dept. of Health, Education, and Welfare, Public Health Service, National Institutes of Health, National Cancer Institute, Division of Cancer Cause and Prevention, Carcinogenesis Testing Program in Bethesda, Md .
Written in English

    Subjects:
  • Carcinogens.,
  • Dyes and dyeing -- Toxicology.,
  • Amines -- Toxicology.

  • Edition Notes

    SeriesCarcinogenesis technical report series ; no. 190, DHEW publication ; no. (NIH) 79-1746, DHEW publication -- no. (NIH) 79-1746.
    The Physical Object
    Pagination97 p. in various pagings :
    Number of Pages97
    ID Numbers
    Open LibraryOL18014061M

    Carcinogenicity Studies with Rodents. If this is not possible because of the large number of animals in a study, animals may be placed on study over several days. for the carcinogenicity.   Three hundred fifty-nine neoplasms of the prepucial and clitoral glands of F rats were reviewed to classify the different types of tumors in relation to the normal anatomy and histology of the glands. Most tumors originated from the acinar or ductal cells, while only one tumor could be found originating from the mesenchymal tissue. They were classified as Cited by: Bioassay of selenium sulfide for possible carcinogenicity (dermal study) [] National Cancer Institute (U.S.). Bethesda, Md.: Dept. of Health and Human Services, Public Health Service, National Institutes of Health,


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Bioassay of p-nitrosodiphenylamine for possible carcinogenicity. by National Cancer Institute (U.S.). Division of Cancer Cause and Prevention. Download PDF EPUB FB2

A bioassay for the possible carcinogenicity of p-nitrosodi­ phenylamine was conducted using Fischer rats and B6C3F1 mice. p-Nitrosodiphenylamine was administered in the feed, at either of two concentrations, to groups of 50 male and 50 female animals of each species.

Twenty animals of each sex and species were placed on test as controls. A bioassay for the possible carcinogenicity of p-nitrosodiphenylamine was conducted using Fisher rats and B6C3F1 mice.

p-Nitrosodiphenylamine was administered in the feed, at either of two concentrations, to groups of 50 male and female animals of each species. Twenty animals of each sex and species were placed on test as controls. Get this from a library.

Bioassay of p-nitrosodiphenylamine for possible carcinogenicity. [National Cancer Institute (U.S.). Division of Cancer Cause and Prevention.]. BIOASSAY OF ANTHRANILIC ACID FOR POSSIBLE CARCINOGENICITY CAS NO.

[National Cancer Institute] on *FREE* shipping on qualifying offers. US Department of Health National Cancer Institute Carcinogenesis Technical Report no. 4to wraps. 92p. Light depository library markings. A bioassay of p-cresidine for possible carcinogenicity was conducted using Fischer rats and B6C3F1 mice.

p-Cresidine was administered in the feed, at either of two concentrations, to groups of 50 male and 50 female animals of each species.

A bioassay of p-cresidine for possible carcinogenicity was con­ ducted using Fischer rats and B6C3F1 mice. p-Cresidine was ad­ ministered in the feed, at either of two concentrations, to groups of 50 male and 50 female animals of each Size: 3MB.

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REPORT ON THE BIOASSAY OF HEXACHLOROETHANE FOR POSSIBLE CARCINOGENICITY. CARCINOGENESIS TESTING PROGRAM DIVISION OF CANCER CAUSE AND PREVENTION' NATIONAL CANCER INSTITUTE, NATIONAL INSTITUTES OF HEALTH.

FOREWORD: This report presents the results of the bioassay of hexa­ chloroethane. Search for books, ebooks, and physical Bioassay of malaoxon for possible carcinogenicity Published: () Bioassays of DDT, TDE, and p, p'-DDE for possible carcinogenicity Published: () Bioassay of dixathion for possible carcinogenicity Published: ( COVID Resources.

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Bioassay of azinphosmethyl for possible carcinogenicity by National Cancer Institute (U.S.). Division of Cancer Cause and Prevention. Publication date TopicsPages:   p-Nitrosodiphenylamine: Target Organs and Levels of Evidence for TR Bioassay of p-Nitrosodiphenylamine for Possible Carcinogenicity (CASRN ) Chemical (Study Title) CASRN Peer Review Date Route/Exposure Levels Study Laboratory; p-Nitrosodiphenylamine A bioassay for the possible carcinogenicity of p-nitrosodiphenylamine was conducted using Fischer rats and B6C3F1 mice.

p-Nitrosodiphenylamine was administered in the feed /to/ 50 male and 50 female animals of each species. Twenty animals of each sex and species were placed on test as controls.

N o data are available in the literature on the carcinogenicity of permethrin in humans. Evidence of permethrin's possible carcinogenicity in humans is derived from bioassays in rodents. Permethrin has been tested for its carcinogenicity in seven chronic carcinogenicity studies using mice and rats.

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of Health, Education, and Welfare, Public Health Service, National Institutes of Health, National Cancer Institute, Division of Cancer Cause and Prevention, Carcinogenesis Testing Program, Description.

Bioassay of tetrachlorvinphos for possible carcinogenicity Bioassay of tetrachlorvinphos for possible carcinogenicity by United States. National Cancer Institute. Carcinogen Bioassay and Program Resources Branch. Publication date Topics Carcinogens, Pesticides Publisher.

Get this from a library. Bioassay of N, N'-dicyclohexylthiourea for possible carcinogenicity. [National Cancer Institute (U.S.).

Division of Cancer Cause and Prevention.; Carcinogenesis Testing Program (U.S.)]. REGULATORY TOXICOLOGY AND PHARMACOLOGY 3, () The Power and Interpretation of the Carcinogenicity Bioassay D. CLAYSON,I D. KREWSKI, AND 1. MUNRO Health Protection Branch, Health and Welfare Canada, Ottawa, Canada Received Carcinogenicity is a major consideration in the assessment of risks due to Cited by: Bioassay of piperonyl butoxide for possible carcinogenicity Item Preview remove-circle Bioassay of piperonyl butoxide for possible carcinogenicity by National Cancer Institute (U.S.).

Division of Cancer Cause and : This volume of the IARC Monographs provides evaluations of the carcinogenicity of polychlorinated biphenyls and polybrominated biphenyls. Polychlorinated biphenyls are a class of aromatic compounds comprising congeners, each containing 1 to 10 chlorine atoms attached to a biphenyl nucleus.

Comparative carcinogenicity of o-toluidine hydrochloride and o-nitrosotoluene in F rats ☆ This publication is dedicated to the founder of the American Health Foundation, Dr. Ernst L. Wynder, on the occasion of the 10th anniversary of the Naylor Dana Institute for Cited by: Sampling and Analytical Methods | N-Nitrosodiphenylamine the agent's possible carcinogenicity has been further investigated.

The results of a study, published inindicated that the agent is carcinogenic to rats but not mice. "Bioassay of p-Nitrosodiphenylamine for Possible Carcinogenicity", NCI: Bethesda, Report CAS no.: Search for books, ebooks, and physical media Search Search for books, articles, library site, almost anything Find Advanced Search Tips Combined Search Books & Media Articles & more.

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Division of Cancer Cause and Prevention. Publication datePages: Myhr, B.C., and Caspary, W.J. Evaluation of the LY mouse lymphoma cell mutagenesis assay: Intralaboratory results for sixty-three coded chemicals tested at Litton Bionetics, I. Abstract.

The preceding paper described our numerical index of carcinogenic potency, the TD 50 and the statistical procedures adopted for estimating it from experimental data. This paper presents the Carcinogenic Potency Database, which includes results of about long-term, chronic experiments of test by: Ursula B.

Kaiser, in The Pituitary (Third Edition), Bioassays for LH and FSH. Bioassays for LH are based on stimulation of testosterone secretion from dispersed Leydig cells. Two types of bioassay used for measurement of serum LH bioactivity include the mouse interstitial cell testosterone assay (MICT) or the rat interstitial cell testosterone assay (RICT) [95].

NTP. TR p-Nitrosodiphenylamine (). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

BioAssay record AID submitted by EPA DSSTox: DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results. Regulatory agencies currently rely on rodent carcinogenicity bioassay data to predict whether or not a given chemical poses a carcinogenic threat to humans.

We argue that it is always more useful to know a chemical's carcinogenic potency (with confidence limits) than to be able to say only qualitatively that it has been found to be a by: N-Nitrosodiethanolamine is a pale yellow, oily liquid nitrosamine with a characteristic odor that is light sensitive and emits toxic fumes of nitrogen oxides when heated to decomposition.

N-Nitrosodi-n-butylamine is primarily used in laboratory research to induce tumors in experimental animals, but is also used as an intermediate in the. RPA correlated very well with carcinogenicity for both incubation periods.

Most compounds with an RPA equal to or greater than were known carcinogens. Bioassay of nine coal tar pitch volatile air samples gave RPAs of tobut conclusions were not drawn about the hazard of these mixtures because their carcinogenic potency was not.

“Anything Is Possible” can easily be read without knowing the earlier book, and, in a way, it’s a greater achievement than that “source material.” These Author: Susan Scarf Merrell.

Evaluation of the potential carcinogenicity and genetic toxicity to humans of the herbicide acetochlor. Ashby, L. Kier, Age Wilson, T. Green, PA Lefevre, H.

Tinwell, GA Willis, WF Heydens, and Mjl Clapp Evaluation of the potential carcinogenicity and genetic toxicity to humans of the herbicide acetochlor Anon. Bioassay of 2 Cited by: The committee began meeting in January and selected as its first topic of study and use of the maximum tolerated dose (MTD) in animal bioassays, with emphasis on the relationship between the MTD and the carcinogenic potency of a test chemical.

The general study design for a cancer bioassay was conceived by national cancer institute (NCI) in (Sontag et al. ) and, after some modifications, has been followed ever since. Two species, typically mice and rats, are evaluated in carcinogenicity studies, but consideration needs to be given to the pharmacology of the drug product.

Abstract. Carcinogen bioassay involves exposure of laboratory animals to one or more levels of the test substance, with tumor occurrence rates in the treated groups evaluated relative to those in unexposed controls (Bickis and Krewski, a).Cited by: 7.

N-Nitrosodiphenylamine may be ignited by heat, sparks, or flames; burning with a flare-like effect and the possible production of irritating or poisonous gases. Fires involving N-nitrosodiphenylamine may be extinguished with dry chemical, sand, water spray, fog, or foam.

For a massive fire, use unmanned hose holders.A meta description is an HTML tag in the HTML code of your website, which allows you to customize a section of text that describes the page itself. It plays a role in how your page is seen by search engine crawlers, and how it appears in SERPs.For this reason, the mouse is used much less commonly as a short-term carcinogenicity bioassay than is the rasH2 mouse.

The existence of a non-responder phenotype also emphasizes the importance of genotyping of all study animals prior to the initiation of a carcinogenicity bioassay.